CTLA4 / CD152 Antibody (clone ANC152.2/8H5, Biotin)
Catalogue Number: LS-C134751-LSP
| Manufacturer: | LifeSpan BioSciences Inc. |
| Preservative: | 0.04% Sodium azide |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | CTLA4, CD152, CELIAC3, CD152 antigen, CTLA-4, Celiac disease 3, IDDM12, GRD4, GSE, CD152 isoform |
| Shipping Condition: | RT |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | ANC152.2/8H5 |
| Isotype: | IgG1, kappa |
| Immunogen: | Stimulated human PBL's and human CD152 Ig fusion protein. |
| Application: | ELISA, FC, FA |
Additional Text
Concentration
0.5 mg/ml
Gene ID
1493
Gene Name
CTLA4
Antigen Type
Fusion protein
Purification
Protein A purified
Antibody Clonality
Monoclonal
Storage Note
Store at 4°C. Do not freeze.
Application Notes
Function: ANC152.2 blocks binding of CD152 (CTLA-4) Ig fusion protein to its CD80/CD86 receptor, and has been reported to modulate suppressive function of human T Regulatory Cells in Vitro. ANC152.2 can bind to intracellular CD152 in fixed permeabolized cells. The F(ab')2 form has been used to inhibit proliferation of activated T cells in vitro in a cholera toxin model. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Short Description
CD152 antibody LS-C134751 is a biotin-conjugated mouse monoclonal antibody to human CD152 (CTLA4). Validated for ELISA, Flow and Func.
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