ITGAM / CD11b Antibody (clone M1/70)
Catalogue Number: LS-C357743-LSP
| Manufacturer: | LifeSpan BioSciences Inc. |
| Shelf Life: | 24 months |
| Preservative: | 0.05% Sodium azide |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain |
| Shipping Condition: | RT |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 20 ug |
| Host name: | Rat |
| Clone: | M1/70 |
| Isotype: | IgG2b, kappa |
| Immunogen: | B10 mouse spleen cells enriched for T lymphocytes. |
| Application: | ELISA, FC, IF, IP, IHC-Fr, IHC, FA, Blk |
Additional Text
Gene ID
3684
Antigen Type
Cells
Purification
Protein G purified
Gene Name
ITGAM
Short Description
CD11b antibody LS-C357743 is an unconjugated rat monoclonal antibody to CD11b (ITGAM) from mouse. It is reactive with human, mouse, baboon and other species. Validated for Block, ELISA, Flow, Func, IF, IHC and IP.
Antibody Clonality
Monoclonal
Storage Note
Store at 2°C to 8°C.
Concentration
0.2 mg/ml
Application Notes
CD11b is a cell adhesion molecule that acts as a receptor for cell surface ligands such as intracellular adhesion molecules (ICAMs) or soluble ligands. Integrins are heterodimeric proteins that contain an a chain and b chain. Integrin alpha-M (CD11b) combines with the Integrin beta-2 (CD18) to form a leukocyte-specific integrin referred to as macrophage receptor 1 (Mac-1), or inactivated-C3b (iC3b) receptor 3 (CR3). Integrin alpha-M/beta-2 is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. ELISA: Order BSA-free antibody format for coating.
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