CD47 Antibody (clone B6H12.2)
Catalogue Number: LS-C357794-LSP
| Manufacturer: | LifeSpan BioSciences Inc. |
| Shelf Life: | 24 months |
| Preservative: | 0.05% Sodium azide |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | CD47, CD47 antigen, CD47 molecule, Integrin associated protein, Integrin-associated protein, Leukocyte surface antigen CD47, MER6, Protein MER6, Rh-related antigen, OA3, CD47 glycoprotein, IAP |
| Shipping Condition: | RT |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug, 20 ug |
| Host name: | Mouse |
| Clone: | B6H12.2 |
| Isotype: | IgG1, kappa |
| Immunogen: | Intact CD47 purified from placenta. |
| Application: | FC, IF, IHC-P, WB, IHC, FA, Blk |
Additional Text
Gene ID
961
Antigen Type
Purified protein
Purification
Protein G purified
Gene Name
CD47
Short Description
CD47 antibody LS-C357794 is an unconjugated mouse monoclonal antibody to human CD47. Validated for Block, Flow, Func, IF, IHC and WB.
Antibody Clonality
Monoclonal
Storage Note
Store at 2°C to 8°C.
Concentration
0.2 mg/ml
Application Notes
This antibody reacts with the Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. Functional Activity/blocking: Order BSA/Azide-free format
SUPPORT
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PRODUCT
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DELIVERY
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