ITGB4 / Integrin Beta 4 Antibody (clone UM-A9)

Catalogue Number: LS-C357939-LSP

Manufacturer:	LifeSpan BioSciences Inc.
Shelf Life:	24 months
Preservative:	0.05% Sodium azide
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	ITGB4, CD104, Integrin beta-4, Integrin Beta 4, gp150, CD104 antigen, Integrin beta-4 subunit, Integrin, beta 4
Shipping Condition:	RT
Storage Condition:	2-8°C
Unit(s):	100 ug, 20 ug
Host name:	Mouse
Clone:	UM-A9
Isotype:	IgG2a, kappa
Immunogen:	The human squamous cell carcinoma line (UM-SCC1).
Application:	FC, IF, Blk

Overview

Additional Text

Gene Name

ITGB4

Gene ID

3691

Antigen Type

Cells

Purification

Protein G purified

Short Description

Integrin Beta 4 antibody LS-C357939 is an unconjugated mouse monoclonal antibody to human Integrin Beta 4 (ITGB4). Validated for Block, Flow and IF.

Antibody Clonality

Monoclonal

Storage Note

Store at 2°C to 8°C.

Concentration

0.2 mg/ml

Application Notes

This antibody recognizes a protein of 205kDa, which is identified as integrin beta 4 (ITGB4) and CD104. Its epitope is localized in the extracellular domain of integrin beta 4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. ELISA: Order BSA-free format for coating.

Price

£714.00

-

Quantity
Unit Size

Find out about delivery