BCL2 / Bcl-2 Antibody (aa1-211)

Catalogue Number: LS-C388072-LSP

Manufacturer:LifeSpan BioSciences Inc.
Preservative:0.025% Sodium azide
Physical state:Lyophilized
Type:Polyclonal Primary Antibody - Unconjugated
Alias:BCL2, Apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, B-cell lymphoma protein 2, Bcl-2, PPP1R50
Shipping Condition:RT
Unit(s): 100 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Human partial recombinant protein (aa1-211).
Application: ELISA, IP, WB, FA

Additional Text

Gene ID

596

Antigen Type

Recombinant Protein

Purification

Affinity Purified

Gene Name

BCL2

Short Description

Bcl-2 antibody LS-C388072 is an unconjugated rabbit polyclonal antibody to human Bcl-2 (BCL2) (aa1-211). Validated for ELISA, Func, IP and WB.

Storage Note

Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.

Antibody Clonality

Polyclonal

Application Notes

Immunoreactive BCL2 protein was detected in the neoplastic cells of almost all follicular lymphomas whereas no BCL2 protein was detected in follicles affected by nonneoplastic processes or in normal lymphoid tissue. Every tumor with molecular-genetic evidence of t (14.18) translocation expressed detectable levels of the protein, regardless of whether the breakpoint was located in or at a distance from the gene. Overexpression blocks the apoptotic death of a pro-B-lymphocyte cell line.