TNF Alpha Antibody (aa80-235)

Catalogue Number: LS-C388968-LSP

Manufacturer:LifeSpan BioSciences Inc.
Preservative:0.025% Sodium azide
Physical state:Lyophilized
Type:Polyclonal Primary Antibody - Unconjugated
Alias:TNF, APC1 protein, Cachectin, DIF, TNF Alpha, Tumor necrosis factor-alpha, TNF-alpha, TNF-a, TNFA, Tumor necrosis factor, TNF, macrophage-derived, TNF, monocyte-derived, TNFSF2
Shipping Condition:RT
Unit(s): 100 ug
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Mouse partial recombinant protein (aa80-235).
Application: ELISA, IHC-P, IP, WB, IHC, FA

Additional Text

Gene ID

7124

Antigen Type

Recombinant Protein

Purification

Affinity Purified

Gene Name

TNF

Short Description

TNF Alpha antibody LS-C388968 is an unconjugated rabbit polyclonal antibody to mouse TNF Alpha (aa80-235). Validated for ELISA, Func, IHC, IP and WB.

Storage Note

Prior to reconstitution, 4°C. Following reconstitution store at -20°C. Avoid freeze-thaw cycles.

Antibody Clonality

Polyclonal

Application Notes

Tumor Necrosis Factor alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It binds and functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation and has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.