CD47 Antibody (clone B6H12.2, Azide-free, BSA-free)

Catalogue Number: LS-C389481-LSP

Manufacturer:LifeSpan BioSciences Inc.
Shelf Life:24 months
Preservative:Azide-free
Type:Monoclonal Primary Antibody - Unconjugated
Alias:CD47, CD47 antigen, CD47 molecule, Integrin associated protein, Integrin-associated protein, Leukocyte surface antigen CD47, MER6, Protein MER6, Rh-related antigen, OA3, CD47 glycoprotein, IAP
Shipping Condition:RT
Storage Condition:2-8°C
Unit(s): 100 ug
Host name: Mouse
Clone: B6H12.2
Isotype: IgG1, kappa
Immunogen: Intact CD47 purified from placenta.
Application: FC, IF, IHC-P, WB, IHC, FA, Blk

Additional Text

Concentration

0.5 mg/ml

Gene ID

961

Antigen Type

Purified protein

Purification

Protein G purified

Gene Name

CD47

Short Description

CD47 antibody LS-C389481 is an unconjugated mouse monoclonal antibody to human CD47. Validated for Block, Flow, Func, IF, IHC and WB.

Antibody Clonality

Monoclonal

Storage Note

Store at 2°C to 8°C.

Application Notes

The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. This antibody reacts with the Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction. Functional Activity/blocking: Order BSA/Azide-free format