Progesterone Antibody (clone 6-5E-10B, Azide-free, BSA-free)
Catalogue Number: LS-C391484-LSP
| Manufacturer: | LifeSpan BioSciences Inc. |
| Shelf Life: | 24 months |
| Preservative: | Azide-free |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | RT |
| Storage Condition: | 2-8°C |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | 6-5E-10B |
| Isotype: | IgG1, kappa |
| Immunogen: | Progesterone- 11a-hemisuccinate conjugated to bovine serum albumin (Pr11a-HMS-BSA). |
| Application: | ELISA, RIA, IHC |
Additional Text
Concentration
0.5 mg/ml
Antigen Type
Hapten
Purification
Protein G purified
Short Description
Progesterone antibody LS-C391484 is an unconjugated mouse monoclonal antibody to Progesterone. Validated for ELISA, IHC and RIA.
Antibody Clonality
Monoclonal
Storage Note
Store at 2°C to 8°C.
Application Notes
This mAb is specific for progesterone. It exhibits minimal cross reactivity with related compounds in ELISA. It reacts with Progesterone-11a-HMS-BSA: 100%. 5-beta-Pregnane-3,20-dione: 48%. 5-alpha-Pregnane-3,20-dione: 26.4%. 17-alpha-Hydroxyprogesterone: 2.5% and 20-alpha-Hydroxyprogesterone: 0.04%. Progesterone is a steroid hormone synthesized from the cholesterol derivative, pregnenolone, in the cortex of the adrenal gland. Progesterone is secreted by the corpus luteum and acts to prepare the endometrium for the implantation of a fertilized egg. During pregnancy, it is secreted by the placenta to prevent spontaneous abortion and to stimulate the development of mammary tissue to produce milk. Thus, progesterone plays a central role in the reproductive events associated with the establishment and maintenance of pregnancy. Luteinized theca cells of normal ovary secrete progesterone. The determination of progesterone concentrations in the body fluids is of great value for endocrinological investigations in women. This mAb may prove useful in identification of ovarian tumors. Optimal dilution of the Progesterone antibody should be determined by the researcher. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
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