TNFSF11 / RANKL / TRANCE Antibody (clone R001, Preservative Free)

Catalogue Number: LS-C819140-LSP

Manufacturer:	LifeSpan BioSciences Inc.
Shelf Life:	12 months
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	TNFSF11, CD254, CD254 antigen, HRANKL2, OPTB2, TRANCE, ODF, OPGL, SOdf, Osteoprotegerin ligand, RANKL
Shipping Condition:	RT
Unit(s):	200 ug, 500 ug
Host name:	Rabbit
Clone:	R001
Isotype:	IgG
Immunogen:	Recombinant Human RANKL / OPGL / TNFSF11 / CD254 protein
Application:	ELISA, NT, Blk

Overview

Additional Text

Gene ID

8600

Antigen Type

Recombinant Protein

Purification

Protein A purified

Gene Name

TNFSF11

Short Description

TRANCE antibody LS-C819140 is an unconjugated rabbit monoclonal antibody to human TRANCE (TNFSF11 / RANKL). Validated for Block, ELISA and Neut.

Antibody Clonality

Monoclonal

Storage Note

Store at 2°C to 8°C for up to 1 month. Aliquot and store at -20°C to -80°C for up to 1 year. Avoid freeze/thaw cycles.

Application Notes

Block: In a functional ELISA which immobilized recombinant Human TNFRSF11A at 2ug/ml (100 µL/well) in the plate, the Rabbit anti-Human TNFSF11 Monoclonal Antibody can block the binding of 0.2 ug/ml of recombinant Human TNFSF11 to human TNFRSF11A, the EC50 is 0.48 ug/ml; Immobilized recombinant Human recombinant Human TNFRSF11B at 2 ug/ml in the plate, the Antibody can block the binding of 0.2 ug/ml of recombinant Human TNFSF11 to human TNFRSF11B, the EC50 is 1.02 ug/ml. Neutralization: The neutralization activity of TNFSF11 Neutralizing Antibody is Measured by its ability to neutralize TNFSF11 induced osteoclast-like cell formation in RAW 264. 7 mouse macrophages. The Neutralization titer (IC50) is typically 4-16 ng/mL in the presence of 30 ng/mL Recombinant Human RANKL/OPGL/TNFSF11/CD254. Please Note: Optimal concentrations/dilutions should be determined by the end user.

Price

£311.00

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