Human BMP7 Protein (Recombinant)

Catalogue Number: LS-G133781-LSP

Manufacturer:	LifeSpan BioSciences Inc.
Molecular Weight:	28.8 kDa
Physical state:	Lyophilized
Type:	Other Recombinant Protein
Alias:	BMP7, Bone morphogenetic protein 7, Eptotermin alfa, OP-1, OP1, Osteogenic protein 1, BMP-7
Host Cell:	CHO Cells
Shipping Condition:	RT
Unit(s):	10 ug, 2 ug

Overview

Description

Description: TGF-β family members are key modulators of cell proliferation, differentiation, matrix synthesis, and apoptosis. As implied by their name, BMPs initiate, promote, and regulate the development, growth, and remodeling of bone and cartilage. In addition to this role, BMPs are also involved in prenatal development and postnatal growth, remodeling, and maintenance of a variety of other tissues and organs. BMP-7, also known as osteogenic protein-1 or OP-1, is a potent bone inducing agent, which in the presence of an appropriate osteoconductive carrier (e.g. collagen sponge or synthetic hydroxyapatite) can be used in the treatment of bone defects. A bone-graft substitute, called OP-1TM implant, made of recombinant human BMP-7 associated with bovine bone-derived collagen, has recently been approved by the FDA as a device for treating critical-size bone fractures. The potential use of BMP-7 in dental reconstructive surgeries is currently under investigation. Recombinant Human BMP-7 is a 28.8 kDa homodimeric glycoprotein consisting of two 117 amino acid subunits, which correspond to amino acid residues 315 to 431 of the full-length BMP-7 precursor.

Additional Text

Gene ID

655

Gene Name

BMP7

Storage Note

Store at -20°C. Protect from moisture.

Price

£447.00

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