Catalogue Number: LS-G133824-LSP
| Manufacturer: | LifeSpan BioSciences Inc. |
| Molecular Weight: | 27.1 kDa or 40.0 kDa |
| Physical state: | Lyophilized |
| Type: | Other Recombinant Protein |
| Alias: | RSPO1, CRISTIN3, HRspo1, R-spondin 1, Roof plate-specific spondin-1, RSPONDIN, RSPO, R-spondin-1, R-spondin1, R-spondin homolog, RP11-566C13.1 |
| Host Cell: | CHO Cells |
| Shipping Condition: | RT |
| Unit(s): | 20 ug, 5 ug |
Description: R-Spondin-1 (Rspo-1) belongs to the (Rspo) family of Wnt modulators. Currently, the family consists of four structurally related secreted ligands (Rspo 1-4), all containing the furin-like and thrombospondin structural domains. Rspo-1 is expressed in certain areas of the developing central nervous system, as well as in the adrenal glands, ovary, testis, thyroid, and trachea. Rspo can interact with the Frizzled/LRP6 receptor complex in a manner that stimulates the Wnt/beta-catenin signaling pathway. Recombinant Murine R-Spondin-1 is a 27.1 kDa protein consisting of 245 amino acid residues. Due to glycosylation, R-Spondin-1 migrates at an apparent molecular weight of approximately 40.0 kDa by SDS-PAGE analysis under reducing conditions.
284654
RSPO1
Store at -20°C. Protect from moisture.