Catalogue Number: LS-G19813-LSP
|Manufacturer:||LifeSpan BioSciences Inc.|
|Alias:||CASQ2, Calsequestrin-2, PDIB2, Calsequestrin 2|
|Unit(s):||10 ug, 2 ug, 5 ug|
Description: Calsequestrin is the major calcium storage protein of the sarcoplasmic reticulum. Intraluminar Ca2+ binds to calsequestrin during diastole to prevent Ca2+ precipitation and to lower its free ionic concentration to facilitate efficient storage. During systole, Calsequestrin coordinately releases ~40--50 Ca2+ ions per molecule for each contraction-relaxation cycle by an uncertain mechanism. Calsequestrin has been shown to be of major importance in the regulation of cardiac excitation-contraction coupling.
CASQ2, Calsequestrin-2, PDIB2, Calsequestrin 2