Catalogue Number: LS-G27082-LSP
| Manufacturer: | LifeSpan BioSciences Inc. |
| Shelf Life: | 6 months |
| Molecular Weight: | 17.4 kDa (SDS-PAGE) |
| Physical state: | Lyophilized |
| Type: | Other Recombinant Protein |
| Alias: | TNF, APC1 protein, Cachectin, DIF, TNF Alpha, Tumor necrosis factor-alpha, TNF-alpha, TNF-a, TNFA, Tumor necrosis factor, TNF, macrophage-derived, TNF, monocyte-derived, TNFSF2 |
| Host Cell: | Pichia pastoris |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 unit, 10 units, 50 units |
Description: Tumor Necrosis Factor-Alpha (TNF-Alpha) also known as Cachectin and TNFSF1A, plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune diseases; and in viral, bacterial, fungal, and parasitic infections. Besides inducing hemorrhagic necrosis of tumors, TNF has been found to be involved in tumorigenesis, tumor metastasis, viral replication, septic shock, fever, inflammation, and autoimmune diseases including Crohn's disease, and rheumatoid arthritis as well as graft-versus-host disease.Recombinant rat Tumor Necrosis Factor-Alpha (rrTNF-Alpha) produced in P. pastoris is a glycosylated polypeptide chain containing 157 amino acids. A fully biologically active molecule, rrTNF-Alpha has a molecular mass of 17.4kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques.
7124
TNF
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 2 weeks or at -20°c for up to 3 months.