Human FGF21 Protein (Recombinant His, C-Terminal)
Catalogue Number: LS-G27140-LSP
| Manufacturer: | LifeSpan BioSciences Inc. |
| Shelf Life: | 6 months |
| Molecular Weight: | 23-25 kDa (SDS-PAGE) |
| Physical state: | Lyophilized |
| Type: | Fusion Protein |
| Alias: | FGF21, Fibroblast growth factor 21, FGF-21 |
| Host Cell: | CHO Cells |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 unit, 10 units, 50 units |
Description
Description: FGF-21, also known as fibroblast growth factor-21 and FGFL, is a secreted growth factor belonging to theheparin-binding growth factor family. It is produced by hepatocytes in response to fatty acid stimulation. FGF-21 couples with its co-factor beta-Klotho to signal through FGFR1c and FGFR4. Signal transduction results in insulin-independent uptake of glucose by adipocytes. Clinical administration of FGF-21 induces energy expenditure, fat utilization and lipid excretion.
Additional Text
Gene Name
FGF21
Gene ID
26291
Protein Tag
HIS Tag
Storage Note
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.
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