Human IL-10 Protein (Recombinant)

Catalogue Number: LS-G27195-LSP

Manufacturer:	LifeSpan BioSciences Inc.
Shelf Life:	6 months
Molecular Weight:	18-19 kDa (SDS-PAGE)
Physical state:	Lyophilized
Type:	Other Recombinant Protein
Alias:	IL10, CSIF, GVHDS, IL-10, IL10A, Interleukin-10, Interleukin 10, TGIF
Host Cell:	CHO Cells
Shipping Condition:	Blue Ice
Unit(s):	1 unit, 10 units, 50 units

Overview

Description

Description: Interleukin-10 (IL-10), initially known as Cytokine Synthesis Inhibitory Factor (CSIF), belongs to the IL-10 family and shares more than 80% sequence homology with Epstein-Barr Virus protein BCRFI. It is produced by many immune cells, such as T-cells, macrophages, mast cells, and dendritic cells. It is usually secreted as a homodimer and, upon binding to its receptor, inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and Th2 cells. It also displays ability to suppress Antigen-Presenting Cell (APC) function. The net effect of Interleukin-10 appears to be inhibitory; however, stimulatory effects, such as stimulation of B cell maturation and antibody production, are also reported.

Additional Text

Gene ID

3586

Gene Name

IL10

Storage Note

Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.

Price

£3,401.00

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