Human IL6 / Interleukin 6 Protein (Recombinant)
Catalogue Number: LS-G27203-LSP
| Manufacturer: | LifeSpan BioSciences Inc. |
| Shelf Life: | 6 months |
| Molecular Weight: | 21-23 kDa (SDS-PAGE) |
| Physical state: | Lyophilized |
| Type: | Other Recombinant Protein |
| Alias: | IL6, B-cell stimulatory factor 2, BSF-2, BSF2, CTL differentiation factor, Hybridoma growth factor, IFN-beta-2, Interleukin-6, Interleukin BSF-2, IFNB2, B-cell differentiation factor, CDF, HSF, IL-6 |
| Host Cell: | CHO Cells |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 unit, 10 units, 50 units |
Description
Description: Interleukin-6 (IL-6), also known as BSF-2, CDF and IFNB2, is a pleiotropic cytokine that acts in both pro-inflammatory and anti-inflammatory responses. It is produced mainly by T cells, macrophages, monocytes, endothelial cells and muscle cells. IL-6 binds to IL-6 receptor (IL-6R) to trigger the association of IL-6R with gp130, inducing signal transduction through JAKs and STATs. The biological functions of IL-6 are diverse. It stimulates B cell differentiation and antibody production, myeloma and plasmacytoma growth, as well as nerve cell differentiation. It also acts as a myokine, produced by muscle cells in response to muscle contraction, to be released to the blood stream to help break down fats and improve insulin resistance.
Additional Text
Gene ID
3569
Gene Name
IL6
Storage Note
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.
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