Human PDGF-D Protein (Recombinant)
Catalogue Number: LS-G27246-LSP
| Manufacturer: | LifeSpan BioSciences Inc. |
| Shelf Life: | 6 months |
| Molecular Weight: | 19-21 kDa (SDS-PAGE) |
| Physical state: | Lyophilized |
| Type: | Other Recombinant Protein |
| Alias: | PDGFD, IEGF, MSTP036, PDGF-D, Iris-expressed growth factor, SCDGF-B, SCDGFB |
| Host Cell: | CHO Cells |
| Shipping Condition: | Blue Ice |
| Unit(s): | 10 units, 50 units |
Description
Description: PDGF-DD, also known as platelet-derived growth factor D, IEGF and SCDGFB, is asecreted growth factor belonging to the PDGF/VEGFfamily. It is highly expressed in the heart, pancreas, adrenal glands and ovary. PDGF-DD forms functional homodimers that bind and induce PDGF RBeta homodimers and PDGF Ra/Beta heterodimers that promote intracellular signaling. This plays an important role in the regulation of cell differentiation, migration and survival. It has also been reported that PDGF-DD can induce monocyte and macrophage recruitment, increase interstitial pressure and facilitate wound healing.
Additional Text
Gene Name
PDGFD
Gene ID
80310
Storage Note
Store lyophilized at -70°C for up to 6 months. Upon reconstitution, store at 4°C for up to 1 week or at -20°C for up to 3 months. Avoid repeated freeze-thaw cycles.
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