Mouse FLT3LG / Flt3 Ligand Protein (Recombinant His, C-Terminal)
Catalogue Number: LS-G27262-LSP
| Manufacturer: | LifeSpan BioSciences Inc. |
| Shelf Life: | 6 months |
| Molecular Weight: | 24-30 kDa (SDS-PAGE) |
| Physical state: | Lyophilized |
| Type: | Fusion Protein |
| Alias: | FLT3LG, FL, Flt3 ligand, FLT3L, SL cytokine |
| Host Cell: | CHO Cells |
| Shipping Condition: | Blue Ice |
| Unit(s): | 10 units, 50 units |
Description
Description: Flt3L, also known as Fms-related tyrosine kinase 3 ligand and SL cytokine, is a single-pass type I membrane protein. It is expressed by stromal cells and T cells. Flt3L signals through tyrosine kinase receptor Flt3/Flk2 to stimulate the proliferation of early hematopoietic progenitor cells. It synergizes with other growth factors, such as GM-CSF, IL-3 and CSF, to promote the differentiation of both myeloid and lymphoid cells. Alternative splicing and proteolytic cleavage of membrane-bound Flt3L generates a soluble extracellular domain (ECD) isoform with full biological activity.
Additional Text
Gene ID
2323
Protein Tag
HIS Tag
Gene Name
FLT3LG
Storage Note
Stable at -80°c for up to 6 months. Upon reconstitution, store at 4°c for up to 1 week or at -20°c for up to 2 months.
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