Human IgG1 Fc Protein (Recombinant) (aa100-330)
Catalogue Number: LS-G4088-LSP
| Manufacturer: | LifeSpan BioSciences Inc. |
| Shelf Life: | 3 months |
| Physical state: | Lyophilized |
| Type: | Other Recombinant Protein |
| Host Cell: | human |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
Description
Description: Human IgG Fc region (aa 100-330) containing the hinge sequence. Mutations were made in the CH2 domain of the Fcg2a fragment using site-directed mutagenesis to replace Glu318, Lys320, and Lys322 with Ala residues and to replace Leu235 with Glu to render the Fcg2a fragment ineffective in directing ADCC and CDC to create a Fc immunoligand.
Additional Text
Storage Note
Store lyophilized at -20°C for up to 1 year. Once reconstituted store at 4°C for immediate use, or aliquot and store at -20°C for up to 3 months. Avoid freeze-thaw cycles.
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations