Human CDA / Cytidine Deaminase Protein (Recombinant His)
Catalogue Number: LS-G961-LSP
| Manufacturer: | LifeSpan BioSciences Inc. |
| Type: | Fusion Protein |
| Alias: | CDA, Cytidine aminohydrolase, Cytidine deaminase, Small cytidine deaminase, CDD, Cytosine nucleoside deaminase |
| Host Cell: | E.coli |
| Shipping Condition: | RT |
| Unit(s): | 0.5 mg, 100 ug, 20 ug |
Description
Description: CDA (Cytidine deaminase) is an enzyme that scavenges exogenous and endogenous cytidine and 2-deoxycytidine for uMP synthesis. This protein is one of several deaminases responsible for maintaining the cellular pyrimidine pool. The protein also catalyzes the deamination of chemotherapeutic cytosine nucleoside analogs such as Ara-C and 5-azacytidine, which results in the loss of their cytotoxic and antitumor function. It can form homotetramers and is mainly expressed in granulocytes. Recombinant human CDA protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Additional Text
Gene Name
CDA
Gene ID
978
Concentration
0.5 mg/ml
Protein Tag
HIS Tag
Storage Note
Short term: store at 2°C to 8°C for up to 1 week. Long term: aliquot and store at -20°C to -80°C. Avoid freeze-thaw cycles.
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