Catalogue Number: LS-G98872-LSP
| Manufacturer: | LifeSpan BioSciences Inc. |
| Molecular Weight: | 38.7 kDa |
| Physical state: | Lyophilized |
| Type: | Fusion Protein |
| Alias: | ACVRL1, ALK1, Activin receptor-like kinase 1, ALK-1, ACVRLK1, HHT, HHT2, SKR3, TSR-I, ORW2 |
| Shipping Condition: | Blue Ice |
| Storage Condition: | -70°C |
| Unit(s): | 200 ug |
Description: The secreted recombinant rat ACVRL1/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer comprises 343 amino acids with a predicted molecular mass of 38.7 kDa. As a result of glycosylation, it migrates as an approximately 50-55 kDa band in SDS-PAGE under reducing conditions. A synthetic DNA sequence encoding the rat ACVRL1 (NP_071886.1) extracellular domain (Met 1-Ala 118) was fused with the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.
94
ACVRL1
HIS-Fc Tag
Store at -70°C.