Anti-Human CD194 (CCR4) Mogamulizumab [Clone KW-0761] - Fc Muted™ Biotin
Catalogue Number: LT1006-LET
| Manufacturer: | Leinco Technologies, Inc |
| Type: | Recombinant Monoclonal |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | |
| Clone: | KW-0761 |
| Isotype: | |
| Immunogen: | |
| Application: | ELISA, FC, FA, Depl |
Description
Description: Clone KW-0761 (Mogamulizumab) is a research-grade, afucosylated, humanized monoclonal antibody generated from mouse anti-CCR4 mAb7 that targets human CCR4.1 CC chemokine receptor type 4 (CCR4) is a protein that belongs to the G protein-coupled receptor family and is a receptor for a variety of CC chemokines including MCP-1, MIP-1, RANTES, TARC, and Macrophage-derived chemokine. Chemokines are involved in the development, homeostasis, and function of the immune system and are known to regulate cell trafficking of various types of leukocytes. In a 2018 Phase I clinical trial, Mogamulizumab was found to decrease the number of HTLV-1-infected cells and the levels of inflammatory markers related to HTLV-1-Associated Myelopathy.3
Additional Text
Concentration
0.5 mg/ml
Antibody Clonality
Monoclonal, Recombinant Monoclonal
Storage Note
This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.
SUPPORT
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PRODUCT
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DELIVERY
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