Macrophage Scavenger Receptor Type I (MSR1, CD204, Macrophage Acetylated LDL Receptor I and II, Macrophage Scavenger Receptor Types I and II, phSR1, Scavenger Receptor Class A Member 1, SCARA1, Scavenger Receptor Type A, SRA, Scvr) (MaxLight 550)

Catalogue Number: M1210-04C-ML550-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™550.
Type:Monoclonal Primary Antibody - Conjugated
Alias:macrophage acetylated LDL receptor I and II|macrophage scavenger receptor types I and II|MRS-A|MSR|MSR-A|Scara1|scavenger receptor type A|Scvr|SR-A|SR-AI|SR-AII
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rat
Clone: 10B1015 (2F8)
Isotype: IgG2b
Immunogen: Raw 264 cell line.
Application: FC, IF, IP, WB, IHC, FLISA

Description

Description: MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. The murine scavenger receptor class A (SRA), type I and II is also known as CD204. CD204 is expressed by tissue macrophages and functions both as an endocytic receptor for lipoproteins and as an adhesion receptor for macrophages binding to ligand rich tissues e.g. atherosclerotic lesions. Inhibits the uptake of acetylated low-density lipoproteins and also inhibits divalent cation independent adhesion.

Additional Text

Gene Name

MSR1

Specificity

Recognizes the murine scavenger receptor class A (SRA), type I and II. Reacts with an epitope within SRA that is polymorphic in the SRA from C57BL/6 mice and is therefore unsuitable for use with the C57BL/6 mouse strain.

Purification

Protein G purified

Uniprot ID

P30204

Gene ID

20288

Antibody Clonality

Monoclonal