Macrophages (PE)
Catalogue Number: M1250-01C-PE-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with R-Phycoerythrin (PE). |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | BA4D5 |
| Isotype: | IgG2b |
| Immunogen: | Porcine alveolar macrophages |
| Application: | IP, WB, IHC |
Description
Description: Macrophages and histiocytes, which are widely distributed throughout the body, play a crucial role in the body defense mechanisms. They are heterogenous in morphology, cytochemistry, function and surface antigens. Immunohistochemical labeling with monoclonal antibodies is one of the most specific and reliable techniques for the identification and localization of these cells. Monoclonal antibodies to macrophage and histiocyte surface or cytoplasmic antigens are important for the immunodiagnosis of both benign and malignant histiocytic lesions. They are useful in the investigation of macrophage differentiation and maturation and in the diagnosis of various inflammatory, reactive and neoplastic disorders of macrophages.
Additional Text
Specificity
Recognizes porcine cells of the monocyte/macrophage lineage. Stains macrophages in a range of tissues, including the thymus, spleen periarteriolar lymphoid sheath (PALS), spleen red pulp and the Peyer’s patches. Expression has also been reported on some non-heamatopoietic cells including endothelial cells. Expression of the antigen is increased with maturation, with higher expression on peritoneal and alveolar macrophages. Some expression has also been observed on peripheral blood lymphocytes. Recognizes a 105kD antigen in pig macrophages.
Purification
Protein G purified
Antibody Clonality
Monoclonal
M1250-01C-PE Datasheet
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