MDR3 P-glycoprotein (ATP-binding cassette, sub-family B (MDR/TAP), member 4, ABCB4, PGY3)
Catalogue Number: M2825-18P-USB
| Manufacturer: | United States Biological |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | P3II-26 |
| Isotype: | IgG2b |
| Immunogen: | Fusion protein consisting of a fragment of MDR3 P-gp corresponding to aa629-692. |
| Application: | ICC, WB, IHC |
Description
Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a full transporter and member of the p-glycoprotein family of membrane proteins with phosphatidylcholine as its substrate. The function of this protein has not yet been determined; however, it may involve transport of phospholipids from liver hepatocytes into bile. Alternative splicing of this gene results in several products of undetermined function.
Additional Text
Gene Name
ABCB4
Uniprot ID
P21439
Gene ID
5244
Antibody Clonality
Monoclonal
M2825-18P Datasheet
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