MHC Class 1, HLA G (MaxLight 490)
Catalogue Number: M3886-07A-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 3H2678 (MEM-G/9) |
| Isotype: | IgG1 |
| Immunogen: | Recombinant protein corresponding to human HLA--G refolded with beta 2 microglobulin |
| Application: | FC, IF, IHC, FLISA |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. HLA-G is a non-classical major histocompatibility complex (MHC) molecule. HLA-G expression is restricted to trophoblast cells and some medullary thymic epithelial cells. Several isoforms of the HLA-G molecule exist, which include the membrane bound isoforms HLA-G1 - G4 and soluble isoforms HLA-G5 - G7.
Additional Text
Specificity
Recognizes human MHC Class 1 when associated with beta 2 microglobulin. Does not recognize isoforms HLA-G2, G3, and G4. Reported to recognize the soluble isoform HLA-G5.
Purification
Protein A purified
Antibody Clonality
Monoclonal
M3886-07A-ML490 Datasheet
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