Mammaglobin, polycl.
Catalogue Number: MAM003-0.5-EXA
| Manufacturer: | ExAlpha |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Shipping Condition: | RT |
| Storage Condition: | 2-8°C |
| Unit(s): | 0.5 ml |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | |
| Immunogen: | C-terminal 16 aa peptide sequence of human mammaglobin coupled to KLH as a carrier protein |
| Application: | ELISA, WB, IHC |
Description
Description: Detection of mammaglobin in metastatic mamma carcinoma, differential diagnosis of metastases in sentinel lymph nodes Mammaglobin A is a breast gland associated glycoprotein, distantly related to the secretoglobin family including human Uteroglobin and Lipophilins. Unlike other secretoglobin family members Mammaglobin mRNA seems to be Mamma-specific (exception skin). Mammaglobin has been detected by immunohistochemical approach in intact breast tissue as well as in adenocarcinoma. It seems to be up-regulated in cancer tissues. The monoclonal antibody is suitable for the detection of occult mamma carcinoma cells in sentinel lymph nodes and in peripheral blood. The overall sensitivity of mammaglobin detection on paraffin sections of mamma carcinoma was reported to be >80% (Fanger et al. 2002; Han et al. 2003). 10 KDa Mammaglobin from human breast tissue, no cross-reactivity with mammaglobin B, lipophilin and uteroglobin.
Additional Text
Gene ID
4250
Gene Name
SCGB2A2
Uniprot ID
Q13296
Concentration
50 ug/ml
Purification
Affinity Purified
Storage Note
2-8°C
Application Notes
IHC, ELISA , WB
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations