Biotinylated Human HLA-A*11:01&B2M&RASL11B (AVVGASGVGK) Monomer Protein (MHC-HE003B)

Catalogue Number: MHC-HE003B-KAT

Manufacturer:Kactus
Shelf Life:12 months
Molecular Weight:The protein has a predicted MW of 35.36 kDa (HLA-A*11:01) and 11.9 kDa (B2M) same as Bis-Tris PAGE result.
Physical state:Liquid
Type:Protein - Conjugated
Alias:RAS11B; AVVGASGVGK; RASL11B
Host Cell:E.coli
Shipping Condition:Dry Ice
Unit(s): 100 ug, 500 ug

Description

Description: RAS (H-ras, K-ras, and N-ras), as the second largest mutated gene driver in various human cancers, has long been a vital research target for cancer. Its function is to transform the extracellular environment into a cascade of intracellular signal transduction. RAS mutant protein regulates tumor cell proliferation, apoptosis, metabolism and angiogenesis through downstream MAPK, PI3K and other signaling pathways.

Additional Text

Gene Name

B2M

Gene ID

567

Uniprot ID

P61769

Protein Tag

HIS-AviTag™

Accession Number

AAV53343.1

Storage Note

Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Endotoxin

Less than 1 EU per µg by the LAL method.

Short Description

Recombinant Biotinylated Human HLA-A*11:01&B2M&RASL11B (AVVGASGVGK) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and AVVGASGVGK peptide.

Price
£442.00


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