PE-Labeled Human HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein (MHC-HE005TP)
Catalogue Number: MHC-HE005TP-KAT
MHC-HE005TP Image
MHC-HE005TP Image
1E6 of NY-ESO-1 specific TCR-HEK293T cell line were stained with 100 ul of 5 ug/ml PE-Labeled Human HLA-A*11:01&B2M&KRAS G12V(VVVGAVGVGK) Tetramer Protein (Cat. No. MHC-HE005TP) and non-transfected HEK293T cells and PE-Labeled protein were used as negative control. PE signal was used to evaluate the binding activity.
| Manufacturer: | Kactus |
| Shelf Life: | 6 months |
| Physical state: | Liquid |
| Type: | Protein - Conjugated |
| Alias: | MHC; KRAS; K-Ras 2; KRAS2; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KRAS1; KRAS2; NS; NS3; RASK2; GTPase Kras; KI-RAS; RALD |
| Host Cell: | E.coli |
| Shipping Condition: | Dry Ice |
| Unit(s): | 100 ug, 500 ug |
Description
Description: Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Additional Text
Gene Name
B2M
Gene ID
567
Uniprot ID
P61769
Protein Tag
HIS-AviTag™
Accession Number
AAV53343.1
Storage Note
Valid for 6 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Short Description
Recombinant PE-Labeled Human HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus. PE-Labeled Human HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer is assembled by biotinylated monomer and PE-labeled streptavidin.It contains Gly25-Thr305 (HLA-A*11:01), Ile21-Met119 (B2M) and VVVGAVGVGK peptide.
Endotoxin
Less than 1 EU per µg by the LAL method.
MHC-HE005TP Datasheet
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