Biotinylated Human HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Monomer Protein (MHC-HE012B)

Catalogue Number: MHC-HE012B-KAT

Manufacturer:	Kactus
Shelf Life:	12 months
Molecular Weight:	The protein has a predicted MW of 35.6 kDa (HLA-A*02:01) and 11.9 kDa (B2M) same as Bis-Tris PAGE result.
Physical state:	Liquid
Type:	Protein - Conjugated
Alias:	MHC; HLA-A; P53; TP53; Antigen NY-CO-13; BCC7; FLJ92943; LFS1; TRP53
Host Cell:	E.coli
Shipping Condition:	Dry Ice
Unit(s):	100 ug, 500 ug
Application:	WB

Overview
Datasheets

Description

Description: p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell proliferation and tumor progression. Depending on the p53 mutation, it has been shown to form aggregates leading to negative gain of function of the protein. p53 mutant associated aggregation has been observed in several cancer tissues and has been shown to promote tumor growth.

Additional Text

Gene Name

B2M

Gene ID

567

Protein Tag

HIS-AviTag™

Storage Note

Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Uniprot ID

A0A140T913, P61769

Short Description

Recombinant Biotinylated Human HLA-A*02:01&B2M&P53 WT (HMTEVVRRC) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and HMTEVVRRC peptide.

Endotoxin

Less than 1 EU per µg by the LAL method.

MHC-HE012B Datasheet

MHC-HE012B MSDS

Price

£244.00

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