Biotinylated Human HLA-A*02:01&B2M&CMVpp65 (NLVPMVATV) Monomer Protein (MHC-HE013B)

Catalogue Number: MHC-HE013B-KAT

Manufacturer:	Kactus
Shelf Life:	12 months
Molecular Weight:	The protein has a predicted MW of 35.6 kDa (HLA-A*02:01) and 11.9 kDa (B2M) same as Bis-Tris PAGE result.
Physical state:	Lyophilized
Type:	Protein - Conjugated
Alias:	CMVpp65; NLVPMVATV
Host Cell:	E.coli
Shipping Condition:	RT
Unit(s):	100 ug, 500 ug
Application:	WB

Overview
Datasheets

Description

Description: Human cytomegalovirus (CMV), a β-herpes virus with a double-stranded DNA, infects a wide variety of cells and establishes latency in the host. CMVpp65, a tegument protein of the herpes virus CMV, is the main viral antigen found in peripheral blood mononuclear cells (PBMCs) after viral infection and may activate cell-mediated immunity, accounting for 70-90% of the cytotoxic CD8+ T cells' (CTLs) response to CMV. Among the pp65-derived CTL epitope peptides, the 9-mer peptide 495NLVPMVATV503 (CMVpp65 495-503 peptide) is the most immunogenic T cell epitope predominantly displayed on HLA-A*02:01, the most common MHC-I allele in the population.

Additional Text

Gene Name

B2M

Gene ID

567

Protein Tag

HIS-AviTag™

Uniprot ID

A0A140T913, P61769

Short Description

Recombinant Biotinylated Human HLA-A*02:01&B2M&CMVpp65 (NLVPMVATV) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus.It contains Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and NLVPMVATV peptide.

Storage Note

-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Endotoxin

Less than 1 EU per µg by the LAL method.

MHC-HE013B MSDS

MHC-HE013B Datasheet

Price

£244.00

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