Cynomolgus MICA Protein (MIC-CM10A)
Catalogue Number: MIC-CM10A-KAT
MIC-CM10A Image
MIC-CM10A Image
MIC-CM10A Image
MIC-CM10A Image
The purity of Cynomolgus MICA is greater than 95% as determined by SEC-HPLC.
MIC-CM10A Image
Cynomolgus MICA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
MIC-CM10A Image
Immobilized Cynomolgus MICA, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 64.5ng/ml determined by ELISA (QC Test).
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 33.53 kDa. Due to glycosylation, the protein migrates to 48-58 kDa based on Bis-Tris PAGE result. |
| Physical state: | Lyophilized |
| Type: | Other Recombinant Protein |
| Alias: | Mafa-MIC1; MICA |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA, WB |
Description
Description: MICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig-like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin.
Additional Text
Protein Tag
HIS Tag
Accession Number
AAO24115.1
Short Description
Recombinant Cynomolgus MICA Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu1-Trp284.
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biological Activity
Immobilized Cynomolgus MICA, His Tag at 1Oeg/ml (100Oel/well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.14Oeg/ml determined by ELISA. See testing image for detail.
Endotoxin
Less than 1 EU per µg by the LAL method.
MIC-CM10A Datasheet
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