Cynomolgus MASP2 Protein (MSP-CE102)

Catalogue Number: MSP-CE102-KAT

Manufacturer:	Kactus
Shelf Life:	24 months
Molecular Weight:	The protein has a predicted MW of 46.8 kDa. Due to autocatalytic cleavage, the protein migrates to 21-24 kDa&28-30 kDa based on Bis-Tris PAGE result.
Physical state:	Lyophilized
Type:	Proteases
Alias:	MAP19; MASP-2; MASP1P1; sMap
Host Cell:	E.coli
Shipping Condition:	RT
Unit(s):	100 ug, 500 ug
Application:	ELISA, WB

Overview
Datasheets

Description

Description: The dysregulation of complement cascade leads to unsolicited cytokine storm, inflammation, deterioration of alveolar lining cells, culminating in acquired respiratory destructive syndrome (ARDS). Similar pathogenesis is observed with the middle east respiratory syndrome (MERS), severe acquired respiratory syndrome (SARS), and SARS-CoV-2. Activation of the lectin pathway via mannose-binding lectin associated serine protease 2 (MASP2) is witnessed under discrete viral infections including COVID-19.

Additional Text

Gene Name

MASP2

Protein Tag

HIS Tag

Uniprot ID

A0A2K5UJY0

Gene ID

102131322

Short Description

Recombinant Cynomolgus MASP2 Protein is expressed from E.coli with His tag at the C-Terminus.It contains Thr287-Phe686.

Storage Note

-20 to -80°C for 24 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Biological Activity

Immobilized Cynomolgus MASP2, His Tag at 1Oeg/ml (100Oel/well) on the plate. Dose response curve for Anti-MASP2 Antibody, hFc Tag with the EC50 of 10.4ng/ml determined by ELISA. See testing image for detail.

Endotoxin

Less than 1 EU per µg by the LAL method.

MSP-CE102 Datasheet

MSP-CE102 MSDS

Price

£318.00

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