Human MASP2 Protein (MSP-HE102)

Catalogue Number: MSP-HE102-KAT

Manufacturer:Kactus
Shelf Life:12 months
Molecular Weight:The protein has a predicted MW of 46.9 kDa. Due to autocatalytic cleavage, the protein migrates to 18 kDa&25-30 kDa based on Bis-Tris PAGE result.
Physical state:Lyophilized
Type:Proteases
Alias:MAP19; MASP-2; MASP1P1; sMap
Host Cell:E.coli
Shipping Condition:RT
Unit(s): 100 ug, 500 ug
Application: ELISA, WB

Description

Description: The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood. One case-control study has reported an association between susceptibility to SARS and mannan-binding lectin (MBL) in China. As the downstream protein of MBL, variants of the MBL-associated serine protease-2 (MASP2) gene may be associated with SARS coronavirus (SARS-CoV) infection in the same population.

Additional Text

Protein Tag

HIS Tag

Short Description

Recombinant Human MASP2 Protein is expressed from E.coli with His tag at the C-Terminus.It contains Gly288-Phe686.

UniProt ID

O00187-1

Storage Note

-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Biological Activity

Immobilized Human MASP2, His Tag at 0.2Oeg/ml (100Oel/Well). Dose response curve for Anti-MASP2 Antibody, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA. The affinity constant of 3.08 nM as determined in SPR assay (Biacore T200). See testing image for detail.

Endotoxin

Less than 1 EU per µg by the LAL method.

Price
£318.00


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