Biotinylated Rat MASP2 Protein (Primary Amine Labeling) (MSP-RE102B)

Catalogue Number: MSP-RE102B-KAT

Manufacturer:	Kactus
Shelf Life:	12 months
Molecular Weight:	The protein has a predicted MW of 46.7 kDa. Due to autocatalytic cleavage, the protein migrates to 15-20 kDa&25-30 kDa based on Bis-Tris PAGE result.
Physical state:	Liquid
Type:	Proteases
Alias:	MAP19; MASP-2; MASP1P1; sMap
Host Cell:	E.coli
Shipping Condition:	Dry Ice
Unit(s):	100 ug, 500 ug
Application:	ELISA, WB

Overview
Datasheets

Description

Description: The dysregulation of complement cascade leads to unsolicited cytokine storm, inflammation, deterioration of alveolar lining cells, culminating in acquired respiratory destructive syndrome (ARDS). Similar pathogenesis is observed with the middle east respiratory syndrome (MERS), severe acquired respiratory syndrome (SARS), and SARS-CoV-2. Activation of the lectin pathway via mannose-binding lectin associated serine protease 2 (MASP2) is witnessed under discrete viral infections including COVID-19.

Additional Text

Gene Name

MASP2

Protein Tag

HIS Tag

Gene ID

64459

Uniprot ID

A2VCV7

Short Description

Recombinant Biotinylated Rat MASP2 Protein (Primary Amine Labeling) is expressed from E.coli with His tag at the C-Terminus.It contains Thr287-Phe685.

Storage Note

Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Biological Activity

Immobilized Anti-MASP2 Antibody, hFc Tag at 0.5Oeg/ml (100Oel/well) on the plate. Dose response curve for Biotinylated Rat MASP2, His Tag with the EC50 of 19.3ng/ml determined by ELISA. See testing image for detail.

Endotoxin

Less than 1 EU per µg by the LAL method.

MSP-RE102B Datasheet

MSP-RE102B MSDS

Price

£471.00

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