Rat anti Forssman antigen

Catalogue Number: MUB0610P-NMB

Manufacturer:	Nordic MuBio
Type:	Monoclonal Primary Antibody - Unconjugated
Shipping Condition:	RT
Unit(s):	0.1 mg
Host name:	Rat
Clone:	117C9
Isotype:	IgM
Immunogen:
Application:	IHC-Fr

Overview

Description

Description: The Forssman glycolipid is a glycosylceramide possessing a neutral pentasaccharide head group, referred to as the Forssman antigen (Fa) and is a member of the globoseries glycolipid family. Fa has been identified in a number of mammals and exhibits heterogeneity with respect to developmental and cell-type expression among species. Some studies have reported the presence of the Fa in certain Human embryonic and tumor cells. The majority of Human individuals have undetectable levels of Fa. Gastric and colonic tumors from Fa-negative patients, however, contained relatively high levels of Fa. Moreover, compared with normal lung tissue, many lung cancers contained elevated levels of Fa. These observations arouse interest in Fa for a possible role as a Human tumor antigen.

Additional Text

Gene Name

GBGT1

Antibody Clonality

Monoclonal

Application Notes

117C92 is useful for immuohistochemistry on frozen sections. Optimal antibody dilution should be determined by titRation.

Storage Note

The antibody is shipped at ambient temperature and may be stored at +4°C. For prolonged storage prepare appropriate aliquots and store at or below -20°C. Prior to use, an aliquot is thawed slowly in the dark at ambient temperature, spun down again and used to prepare working dilutions by adding sterile phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. Working dilutions should be stored at +4°C, not refrozen, and preferably used the same day. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance or the concentration of the product.

Uniprot ID

Q8VI38

Gene ID

227671

Price

£359.00

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