Coronavirus COVID-19 Recombinant SARS-Cov-2 Nucleocapsid protein, His-tagged

Catalogue Number: N-196V-CRE

Manufacturer:Creative BioMart
Shelf Life:12 months
Molecular Weight:47.08 KDa
Type:Other Recombinant Protein
Host Cell:Baculovirus-Insect cells
Shipping Condition:Blue Ice
Unit(s): 1 mg, 100 ug

Description

Description: Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.