Imatinib Mesylate

Catalogue Number: N-3020-1-RPE

Manufacturer:rPeptide
Physical state:Lyophilized
Type:Kinase Inhibitors
Shipping Condition:RT
Unit(s): 20 mg

Description

Description: Tyrosine kinase inhibitor specific for bcr-abl (IC50 = 38 nM)1, PDGF-R (IC50 = 0.3 µM)1 and c-kit (IC50 = 0.1 µM)2. It is a clinically useful anti-cancer drug approved for the treatment of chronic myelogenous leukemia, gastrointestinal stromal tumors as well as several other cancers3. Lowers Amyloid Beta levels by indirect inhibition of gamma-secretase without inhibiting gamma-secretase processing of Notch14.