Imatinib Mesylate
Catalogue Number: N-3020-2-RPE
| Manufacturer: | rPeptide |
| Physical state: | Lyophilized |
| Type: | Kinase Inhibitors |
| Shipping Condition: | RT |
| Unit(s): | 100 mg |
Description
Description: Tyrosine kinase inhibitor specific for bcr-abl (IC50 = 38 nM)1, PDGF-R (IC50 = 0.3 µM)1 and c-kit (IC50 = 0.1 µM)2. It is a clinically useful anti-cancer drug approved for the treatment of chronic myelogenous leukemia, gastrointestinal stromal tumors as well as several other cancers3. Lowers Amyloid Beta levels by indirect inhibition of gamma-secretase without inhibiting gamma-secretase processing of Notch14.
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