FK-506
Catalogue Number: N-3024-2-RPE
| Manufacturer: | rPeptide |
| Physical state: | Lyophilized |
| Type: | Phosphatase Inhibitors |
| Shipping Condition: | RT |
| Unit(s): | 100 mg |
Description
Description: FK-506 induces immunosuppression by inhibiting T cell proliferation. Inhibits FKBP12 and calcineurin (IC50ca. 1 nM)1. Reduces neuroinflammation and neuro-degeneration in an alpha-synuclein-based rat model of Parkinson's disease2. Increases the rate of axonal regeneration following crush injury in a rat model3. Cell permeable.
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