TRO 19622

Catalogue Number: N-3029-1-RPE

Manufacturer:rPeptide
Physical state:white crystalline powder
Type:Other Inhibitors
Shipping Condition:RT
Unit(s): 5 mg

Description

Description: Neuroregenerative and neuroprotective agent acting at components of the mitochondrial permeability transition pore (MPTP)1. Rescues motor neurons from axotomy-induced cell death and promotes nerve regeneration following sciatic nerve crush in mice. Reduces ROS and NLRP3 inflammasome activation in a mouse model of intracerebral hemorrhage2. Inhibits MPTP opening and protects neurons from apoptosis3. Induces oligodendrocyte maturation in culture and promotes myelin regeneration in vivo in a rodent model4.