C16

Catalogue Number: N-3030-1-RPE

Manufacturer:rPeptide
Physical state:Orange powder
Type:Kinase Inhibitors
Shipping Condition:RT
Unit(s): 5 mg

Description

Description: Inhibits RNA-dependent protein kinase (PKR, IC50 = 210 nM)1. Inhibits ER stress-induced neuronal damage2. Reduces brain PKR activation in vivo3. Prevents apoptosis and IL-1 Beta production in an acute excitotoxic and neuroinflammatory rat model4. Prevents Beta-amyloid peptide-induced inflammation in primary murine mixed co-cultures5. Cell permeable.