Catalogue Number: N100M-EXA
| Manufacturer: | ExAlpha |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | p107; Retinoblastoma-like protein 1; PRB1; 107 kda retinoblastoma-associated protein |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | KAB6 |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | WB |
Description: P107 is related both in structure and function to the retinoblastoma tumor suppressor protein and p130 (collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p107 converts E2F transcription factors from transcriptional activators to transcriptional repressors.
RBL1
P28749
5933
Protein A/G Purified
Monoclonal
Western Blots at 1:1000
Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles