Mouse anti Human p107

Catalogue Number: N100M-EXA

Manufacturer:ExAlpha
Type:Monoclonal Primary Antibody - Unconjugated
Alias:p107; Retinoblastoma-like protein 1; PRB1; 107 kda retinoblastoma-associated protein
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Mouse
Clone: KAB6
Isotype: IgG1
Immunogen:
Application: WB

Description

Description: P107 is related both in structure and function to the retinoblastoma tumor suppressor protein and p130 (collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p107 converts E2F transcription factors from transcriptional activators to transcriptional repressors.

Additional Text

Gene Name

RBL1

Uniprot ID

P28749

Gene ID

5933

Purification

Protein A/G Purified

Antibody Clonality

Monoclonal

Application Notes

Western Blots at 1:1000

Storage Note

Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles