Mouse anti Human p130
Catalogue Number: N105M-EXA
| Manufacturer: | ExAlpha |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | p130; Retinoblastoma-like protein 2; RBR-2; PRB2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | KAB40 |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | WB |
Description
Description: P130 is related both in structure and function to the retinoblastoma tumor suppressor protein and p107(collectively known as pocket proteins) and are known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S-phase of the cell cycle. Binding of p130 converts E2F transcription factors from transcriptional activators to transcriptional repressors. This antibody recognizes both the phosphorylated and unphosphorylated forms of p130 at a MW of 130kDa.
Additional Text
Gene Name
RBL2
Uniprot ID
Q08999
Gene ID
5934
Purification
Protein A/G Purified
Antibody Clonality
Monoclonal
Application Notes
Western Blots at 1:1000
Storage Note
Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
SUPPORT
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PRODUCT
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DELIVERY
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