NKR2B4 (Natural Killer Cell Receptor 2B4, NK Cell Type I Receptor Protein 2B4, 2B4, CD244 Molecule Natural Killer Cell Receptor 2B4, h2B4, CD244, NK Cell Activation Inducing Ligand, NAIL, Nmrk, SLAMF4) (FITC)
Catalogue Number: N2839-20H-FITC-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with fluorescein isothiocyanate (FITC). |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 2B4.69 |
| Isotype: | IgG1 |
| Immunogen: | CD244 Fusion protein. |
| Application: | IP |
Description
Description: The glycoprotein NKG2B4 is a member of the SLAM family of receptors which is expressed on natural killer (NK) cells, gamma delta T cells, CD14+ monocytes, and a subset of CD8+ T cells. NKG2B4 was originally identified as an activating receptor on NK cells, although recent studies suggest that the receptor may have a wide range of activities including NK cell activation, costimulation, or even inhibition, depending on the cell type and stage of differentiation. The ligand of 2B4 is CD48, a GPI-anchored membrane protein also belonging to the SLAM family.
Additional Text
Specificity
Recognizes the human natural killer receptor 2B4 (NKG2B4).
Purification
Protein G purified
Antibody Clonality
Monoclonal
N2839-20H-FITC Datasheet
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