Native Bovine Phosphodiesterase II

Catalogue Number: NATE-0518-CRZ

Manufacturer:Creative Enzymes
Type:Other Enzymes
Shipping Condition:Dry Ice
Unit(s): 10 U

Description

Description: Phosphodiesterase (PDE) is any enzyme that is used to breaks phosphodiester bonds. The enzyme acts on poly (A), poly (U), and poly (I). Native DNA and poly (C) are quite resistant to the action of this enzyme. Hydrolyzes RNA, RNA-Core, 3'-alkyl-and

Additional Text

CAS Number

9068-54-6

Short Description

Phosphodiesterase (PDE) is any enzyme that is used to breaks phosphodiester bonds. It is a membrane-bound glycoprotein that is used to catalyze the hydrolysis of various nucleotide polyphosphates. Phosphodiesterase II has been used in the enzymatic digestions of purified proteins such as the P8-dGMP complex. Bovine spleen phosphodiesterase has been used to digest N-cadherin. The product has been used in the characterization of polynucleotide chain length, base composition, and identity of terminal nucleotide. The enzyme has also been used in excision of pyridyloxobutyl (POB) base adducts from DNA. Furthermore, it has been used along with micr oc occal endonuclease to hydrolyze purified DNA to 3-nucleoside monophosphates.

Biological Activity

>1.2 u/mg