2-Fluoro-ATP, (2F-ATP)

Catalogue Number: NU-145S-JEN

Manufacturer:Jena Bioscience
Shelf Life:12 months
Ph:7.5 +/-0
Physical state:Solution
Type:Nucleotides
Shipping Condition:Blue Ice
Unit(s): 10 ul

Description

Description: Figure 1A: Schematic representation of the secondary structure of the Gswapt. The stems are named in blue and the loops are named in green. All fluorinated bases are labeled in red. Figure 1B: 10% PAA-Gel of the transcription samples containing from left to right: low range ssRNA-marker, transcription with unlabeled dNTPs, 15N-UTP, 15N-GTP, 2F-ATP, 15N-UTP-GTP + 2F-ATP. Figure 1C: CD-melting curve of the Gswapt in the ligand bound state. The black curve represents the unlabeled RNA and the green curve represents the 19F-labeled RNA. The melting curves were recorded in the absence (left) and presence (right) of the ligand. Figure 1D: 1H-15N-HSQC of the Gswapt. The spectrum of the unlabeled RNA is shown on the top and the spectrum of the 19F-labeled RNA is shown at the bottom.

Additional Text

Concentration

100-110 mM

Short Description

2-Fluoro-adenosine-5'-triphosphate, Sodium salt

Smile String

Fc1nc(N)c2c(n(cn2)[C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)n1

Molecular Weight

525.17 g/mol (free acid)

Molecular Formula

C10H15N5O13P3F (free acid)

CAS Number

1492-62-2