Guanosine-3',5'-bisdiphosphate, (ppGpp)
Catalogue Number: NU-884L-JEN
| Manufacturer: | Jena Bioscience |
| Shelf Life: | 12 months |
| Ph: | 7.5 +/-0 |
| Physical state: | Solution |
| Type: | Nucleosides |
| Shipping Condition: | Blue Ice |
| Unit(s): | 5 x 10 ul |
Description
Description: (p)ppGpp (collective for ppGpp and pppGpp) is a nucleotide based second messenger and a key regulator of stringent stress response in many bacteria[1]. During nutritional starvation (p)ppGpp initiates the switch from bacterial growth into survival mode. Growth is arrested as (p)ppGpp binds RNA polymerase (RNAP) leading to repressed transcription rate of stable RNA (rRNA, tRNA). Instead, transcription of genes involved in biosynthesis of amino acids is enhanced, leading to prolonged survival[2].
Additional Text
Concentration
100-110 mM
Short Description
Guanosine-3',5'-tetraphosphate, Lithium salt
Smile String
[nH]1c(N)nc2n([C@H]3[C@H](O)[C@@H]([C@H](O3)COP(=O)(O)OP(=O)(O)O)OP(=O)(O)OP(=O)(O)O)cnc2c1=O
Molecular Weight
603.16 g/mol (free acid)
Molecular Formula
C10H17N5O17P4 (free acid)
NU-884L MSDS
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations