Occludin (MaxLight 650)
Catalogue Number: O5202-ML650-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with MaxLight™650. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 3G217 |
| Isotype: | IgG1, kappa |
| Immunogen: | GST fusion protein consisting of the C-terminal region (~150aa) of human occludin. Species Sequence Homology: Bacteria, C.elegans, fish, guinea pig |
| Application: | ICC, IF, WB, FLISA |
Description
Description: MaxLight™ 650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. Occludin is localized at tight junctions of both epithelial and endothelial cells and is highly expressed in kidney and has not been detected in testis. On the cytoplasmic surface of occludin, a domain within the C-terminal 150 residues has been shown to bind directly to the well-characterized tight junction protein zona occludens 1 (ZO-1).
Additional Text
Specificity
Recognizes mammalian Occludin Protein. Species Crossreactivity: human, mouse, rat and canine
Purification
Protein A purified
Antibody Clonality
Monoclonal
O5202-ML650 Datasheet
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