HSP40 antibody

Catalogue Number: ORB151181-BOR

Manufacturer:Biorbyt
Type:Polyclonal Primary Antibody - Conjugated
Alias:DnaJ (HSP40) homolog subfamily B member 1 Antibody, DNAJ1 Antibody, DNAJB1 Antibody, HDJ1 Antibody, HSPF1 Antibody
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype:
Immunogen: Recombinant purified full-length human HSP40 (no tags)
Application: ICC, IF, IP, WB

Additional Text

Molecular Weight

40kDa

Gene Name

DNAJB1

Uniprot ID

P25685

Gene ID

3337

Note

For research use only.

Antibody Clonality

Polyclonal

Storage Note

4°C

Short Description

Rabbit polyclonal to Hsp40 (ATTO-488). DnaJ/Hsp40 proteins have been preserved throughout evolution and are important for protein translation, folding, unfolding, translocation, and degradation, primarily by stimulating the ATPase activity of chaperone proteins, Hsp70s. Because the ATP hydrolysis is essential for the activity of Hsp70s, DnaJ/Hsp40 proteins actually determine the activity of Hsp70s by stabilizing their interaction with substrate proteins. DnaJ/Hsp40 proteins all contain the J domain through which they bind to Hsp70s. Hsp40, also known as HDJ1, is a basic mammalian 40kDa heat shock protein which is not only homologous to the bacterial heat shock protein (DnaJ), but also yeast DnaJ-related proteins such as SCJ1, Sec63/Npl1, YDJ1 and SIS1 (2-5). Hsp 40 is inducible by stress including heat after which is moves from the cytoplasm to the nucleus and nucleoli; an intracellular pattern similar to Hsc70/Hsp70, the mammalian homologues of the bacterial heat shock protein, DnaK.